PCL-PEG-FITC, MW x 5K, n 5K is a fluorescent amphiphilic block copolymer composed of poly(ε-caprolactone), polyethylene glycol, and a fluorescein isothiocyanate (FITC) fluorescent label. The equal 5K PCL and 5K PEG blocks provide balanced hydrophobic-hydrophilic character for self-assembly, while FITC enables fluorescence-based visualization and tracking.
Key Features and Benefits
- Fluorescent Amphiphilic Copolymer: Integrates hydrophobic PCL, hydrophilic PEG, and an FITC fluorescent label.
- PCL MW 5K: Provides a biodegradable hydrophobic segment for nanoparticle or micelle core formation and hydrophobic cargo incorporation.
- PEG MW 5K: Provides a hydrophilic segment specifically for aqueous compatibility, surface hydration, and steric stabilization.
- Balanced Block Ratio: Equal PCL and PEG molecular weights provide balanced hydrophobic and hydrophilic character for amphiphilic assembly.
- FITC Fluorescence: Provides green fluorescence suitable for visualization and fluorescence-based tracking of polymer-containing formulations.
- Carrier Tracking: Enables investigation of nanoparticle localization, cellular uptake, intracellular trafficking, and polymer distribution.
Applications
- Fluorescent Nanoparticles: Preparation of FITC-labeled polymeric nanoparticles, micelles, and related assemblies.
- Drug Delivery Research: Enables fluorescence-based tracking of polymeric carriers and drug delivery systems.
- Cellular Uptake Studies: Supports fluorescence microscopy and evaluation of polymer or nanoparticle internalization.
- Biodistribution Research: Enables tracking of fluorescent polymer carriers in suitable experimental models.
- Biomaterial Imaging: Supports visualization of polymer localization and transport in biomaterial and tissue-engineering studies.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry, light-protected conditions.
- Handling: Protect from light, moisture, and excessive heat to preserve polymer integrity and fluorescence performance.
This product combines balanced PCL and PEG blocks with FITC fluorescence and specifically supports traceable amphiphilic polymer assemblies for nanoparticle imaging, cellular uptake, localization, and drug delivery research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.