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HomePolyethylene Glycol PEG LinkersTetrazine PEGTetrazine-PEG-Amine Methyltetrazine-PEG12-amine HCl salt
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Methyltetrazine-PEG12-amine HCl salt

Catalog #: AP13924
Name: Methyltetrazine-PEG12-amine HCl salt
Chemical Formula: C37H64N6O13
Molecular Weight: 800.948
CAS: nan
Purity: ≥95%
Availability: In Stock

Methyltetrazine-PEG12-amine HCl salt

$360.00 – $1,280.00

Methyltetrazine-PEG12-amine HCl salt is a PEG12 linker with a methyltetrazine group and amine handle, especially ideal for copper-free click chemistry, protein labeling, and bioconjugation.

UnitPriceQuantity
100mg$360
250 mg$690
500 mg$1280

Would you like to inquire about bulk pricing?

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SKU: AP13924 Category: Tetrazine-PEG-Amine
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  • Description
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Description

Methyltetrazine-PEG12-amine HCl Salt

This product is a heterobifunctional linker with a methyltetrazine group, a PEG12 spacer, and a terminal amine provided as a hydrochloride salt. The methyltetrazine reacts ultrafast with trans-cyclooctene (TCO) specifically through copper-free IEDDA ligation. The amine couples efficiently with carboxyls or activated esters, while the PEG12 chain improves solubility, flexibility, and spacing, making this reagent highly versatile for bioconjugation and drug delivery.

Key Features and Benefits

  • Methyltetrazine Group: Enables rapid, copper-free IEDDA ligation with TCO.

  • Amine Group: Couples readily with carboxyls or NHS esters.

  • PEG12 Spacer: Provides excellent solubility, long spacing, and reduced steric hindrance.

  • HCl Salt Form: Improves stability and handling.

  • High Purity: Produced to ≥95% purity for reproducibility.

Applications

  • Bioconjugation: Links TCO-modified and amine-containing biomolecules.

  • Protein and Antibody Labeling: Adds dual reactive handles for multifunctional modifications.

  • Probe Development: Builds tetrazine-based probes for imaging and diagnostics.

  • Drug Delivery: Functions as a modular linker in therapeutic systems.

Storage and Handling

  • Storage: Store at –20 °C in a sealed, desiccated container.

  • Handling: Prepare fresh solutions before use; avoid repeated freeze–thaw cycles.

This product integrates ultrafast tetrazine–TCO ligation with amine coupling in a long PEG scaffold, specifically offering a powerful tool for conjugation workflows.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.

Shipping & Delivery
Ships within: 24 hours
Storage condition: -20 ° C
Shipping: Ambient Temperature

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