Methyltetrazine-PEG12-Amine
Overview: Methyltetrazine-PEG12-Amine is a versatile tetrazine linker used for chemical labeling and bioconjugation. Featuring a tetrazine group linked to a polyethylene glycol (PEG) spacer and an amine group, this reagent is ideal for a range of applications requiring precise and efficient conjugation.
Key Features:
- Tetrazine Group: Facilitates rapid and specific click chemistry reactions, particularly with trans-cyclooctene (TCO) and other dienophiles.
- PEG Spacer: The PEG12 linker enhances solubility, flexibility, and reduces steric hindrance, improving the efficiency of the conjugation process.
- Amine Group: Provides a reactive site for further conjugation or labeling with other functional groups.
Applications:
- Protein and Peptide Labeling: Enable precise tagging and tracking of proteins and peptides.
- Cellular Imaging: Improve imaging techniques by incorporating into cellular assays.
- Biochemical Studies: Utilize in various biochemical applications where efficient and specific conjugation is required.
Benefits:
- Efficient Conjugation: The tetrazine-alkyne click chemistry provides a highly efficient and specific labeling method.
- Enhanced Solubility: PEG12 spacer ensures better solubility and reduces potential interference in biological systems.
- Versatility: Amine group allows for further modifications and functionalizations, adding flexibility to experimental designs.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
