DBCO-PEG23-amine is a bifunctional DBCO linker molecule with an amine group on one end and a Dibenzocyclooctyne (DBCO) moiety on the other. The amine group allows conjugation to carboxyl groups, while the DBCO moiety enables copper-free click chemistry reactions with azide-containing molecules. The polyethylene glycol (PEG) spacer enhances solubility and reduces immunogenicity.
Introduction to the application:
In pharmaceutical research and development, DBCO-PEG23-amine serves as a versatile linker for bioconjugation and drug delivery. Its unique characteristics enable the creation of targeted therapeutics and diagnostic agents with improved pharmacokinetics, reduced side effects, and enhanced efficacy. DBCO-PEG23-amine is widely applied in the synthesis of antibody-drug conjugates, targeted nanoparticles, and molecular imaging probes, advancing the fields of oncology, immunology, and molecular biology.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
