cKK-E12

cKK-E12 Ionizable Lipomer, CAS 1432494-65-9, is an advanced lipid nanoparticle used for targeted gene therapy and drug delivery. It combines the cKK-E12 peptide, which binds specifically to integrin αvβ6 receptors on cancer cells, with ionizable lipids that aid in delivering mRNA, siRNA, and other therapeutic agents.

Key Features:

• Ionizable Lipid: Activates under acidic conditions, aiding in endosomal escape and efficient delivery into cells.
• Targeted Delivery: The cKK-E12 peptide enables precise targeting of cancer cells, reducing off-target effects.
• Enhanced Stability: The lipomer structure improves the stability and bioavailability of encapsulated nucleic acids.

Applications:

1. Gene Therapy: Delivers mRNA and siRNA directly to targeted cells, making it ideal for cancer treatment and genetic disorders.
2. Drug Delivery: Efficiently transports therapeutic agents to specific disease sites, enhancing efficacy and minimizing side effects.
3. Molecular Imaging: Allows for selective targeting in diagnostic imaging, improving detection of cancer cells.

cKK-E12 Ionizable Lipomer offers a powerful platform for precise and efficient delivery of genetic therapies, enhancing outcomes in cancer treatment and beyond.