C12-200 is a branched ionizable potent branched tail fat. LNP compositions have been shown to efficiently transport biologically active substances such as small molecule drugs, proteins and nucleic acids into cells and/or intracellular compartments. And it is used in combination with other lipids to form lipid nanoparticles (LNPs) to develop lipidoid nanoparticles for siRNA, mRNA and vaccine delivery. The C12-200 formulation increased the potency of erythropoietin-mRNA-loaded C12-200 lipid nanoparticles by 7-fold relative to previous formulations for siRNA delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.