BCN-endo-PEG3-Maleimide (CAS: 2141976-33-0)
Description:
BCN-endo-PEG3-Maleimide, also known as endo-BCN-PEG3-mal, is a versatile linker used in bioconjugation and click chemistry. It combines a BCN (bicyclo[6.1.0]non-4-yne) group with a maleimide group, connected by a PEG3 spacer for flexibility and solubility.
Key Features:
- BCN Group: Enables copper-free click chemistry through strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.
- Maleimide Group: Reacts specifically with thiol groups, allowing for efficient conjugation to cysteine residues in proteins and peptides.
- PEG3 Spacer: Increases solubility and reduces steric hindrance, making it suitable for sensitive conjugation processes.
Applications:
- Bioconjugation: Useful for linking proteins, peptides, or other biomolecules.
- Drug Development: Assists in creating complex drug molecules and bioconjugates.
- Nanotechnology: Supports the functionalization of nanoparticles for targeted delivery.
- Material Science: Contributes to designing materials with unique functional properties.
Storage:
Store at -80°C to maintain stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
