Product Name: 8-Arm PLGA-SH, MW 40K
Polymer Composition: 8-Arm Poly(lactic-co-glycolic acid)-Thiol
8-Arm PLGA-SH, MW 40K is a high-molecular-weight eight-arm star-shaped biodegradable polyester with thiol groups modified at each arm terminus. Built upon a central polyol core, this multi-branched scaffold provides a higher density of reactive thiol sites than linear PLGA. The polymer exhibits favorable biocompatibility and adjustable degradation rates. Terminal thiol (-SH) groups can participate in thiol-maleimide click reactions, thiol-ene polymerization and disulfide bond formation, allowing efficient conjugation with maleimide-functionalized biomolecules, gold nanoparticles and other thiol-reactive substrates. It is widely applied in long-acting nanoparticle fabrication, bioligand immobilization, redox-responsive hydrogel construction and sustained drug delivery research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.