PLGA Acid Capped (PLGA-COOH, 85:15), MW 2K

PLGA Acid Capped (PLGA-COOH, 85:15), MW 2K is a low-molecular-weight, carboxyl-terminated poly(D,L-lactide-co-glycolide) random copolymer with a lactide to glycolide molar ratio of 85:15. This biodegradable polymer features reactive terminal carboxylic acid functional groups, enabling efficient EDC/NHS-mediated bioconjugation with amine-containing small molecules, peptides, proteins and targeting ligands for functional biomaterial modification. The low molecular weight structure facilitates rapid hydrolytic degradation, making it highly suitable for constructing short-term controlled drug delivery systems. It exhibits excellent biocompatibility and undergoes complete in vivo degradation into non-toxic lactic acid and glycolic acid. Supplied as white amorphous powder, the polymer is soluble in common organic solvents including DCM, chloroform, THF and acetone. For maximum stability, store the product in a sealed container at -20°C under dry and dark conditions.