Ultimate Guide to t-Boc-Aminooxy-pentane-azide
t-Boc-Aminooxy-pentane-azide is a crucial reagent in bioconjugation and click chemistry, featuring a t-Boc-protected aminooxy group, a pentane spacer, and an azide group. This compound is essential for precise biomolecule labeling, stable conjugate formation, and controlled payload release.
Key Features
- t-Boc Protection: Shields the aminooxy group for controlled reactions.
- Pentane Spacer: Offers flexibility and distance between functional groups.
- Azide Group: Enables copper-free click chemistry.
- Aminooxy Aldehyde Oxime Conjugation: Facilitates stable bonding with aldehyde groups and controlled release of payloads.
Applications
- Bioconjugation: Links biomolecules for enhanced stability and specificity.
- Click Chemistry: Forms robust bonds through copper-free reactions.
- Controlled Payload Release: Utilizes oxime chemistry for precise and controlled release of therapeutic payloads.
- Drug Development: Assists in creating stable drug conjugates with controlled release mechanisms.
Advantages
- High Stability: Ensures reliable conjugate formation.
- Versatility: Suitable for various biomolecules and conditions.
- Enhanced Specificity: Provides precise labeling and targeting.
- Controlled Release: Allows for the regulated release of payloads through oxime bond cleavage.
How to Use
- Preparation: Dissolve in appropriate solvents.
- Reaction: Optimize pH and temperature for effective bioconjugation.
- Purification: Use standard techniques to isolate the desired product.
- Storage: Store in a cool, dry place to maintain stability.
t-Boc-Aminooxy-pentane-azide
t-Boc-Aminooxy-pentane-azide is a crucial reagent in bioconjugation and click chemistry, featuring a t-Boc-protected aminooxy group, a pentane spacer, and an azide group. This compound is essential for precise biomolecule labeling, stable conjugate formation, and controlled payload release.
Key Features
- t-Boc Protection: Shields the aminooxy group for controlled reactions.
- Pentane Spacer: Offers flexibility and distance between functional groups.
- Azide Group: Enables copper-free click chemistry.
- Aminooxy Aldehyde Oxime Conjugation: Facilitates stable bonding with aldehyde groups and controlled release of payloads.
Applications
- Bioconjugation: Links biomolecules for enhanced stability and specificity.
- Click Chemistry: Forms robust bonds through copper-free reactions.
- Controlled Payload Release: Utilizes oxime chemistry for precise and controlled release of therapeutic payloads.
- Drug Development: Assists in creating stable drug conjugates with controlled release mechanisms.
Advantages
- High Stability: Ensures reliable conjugate formation.
- Versatility: Suitable for various biomolecules and conditions.
- Enhanced Specificity: Provides precise labeling and targeting.
- Controlled Release: Allows for the regulated release of payloads through oxime bond cleavage.
How to Use
- Preparation: Dissolve in appropriate solvents.
- Reaction: Optimize pH and temperature for effective bioconjugation.
- Purification: Use standard techniques to isolate the desired product.
- Storage: Store in a cool, dry place to maintain stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
