Tos-PEG3-Tos
This product is a homobifunctional PEG3 linker with dual tosyl groups that serve as reactive leaving groups for substitution with nucleophiles. The PEG3 spacer enhances solubility and flexibility, making it an especially versatile intermediate for PEGylation, bioconjugation, and polymer modification.
Key Features and Benefits
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Dual Tosyl Groups: Highly reactive leaving groups for substitution with a variety of nucleophiles.
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PEG3 Spacer: Enhances solubility and reduces steric hindrance during reactions.
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Homobifunctional Design: Enables crosslinking or bridging of biomolecules and polymers.
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Synthetic Versatility: Useful for generating PEG-diamines, PEG-dithiols, and other derivatives.
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High Purity: Produced to ≥95% purity for consistent and reproducible results.
Applications
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PEG Derivatization: Converts to bifunctional PEG linkers with diverse terminal groups.
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Bioconjugation: Precursor for PEG-based crosslinkers in drug delivery and probe development.
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Polymer and Surface Modification: Functionalizes polymers, nanoparticles, and surfaces to improve biocompatibility.
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Organic Synthesis: Acts as a modular intermediate for advanced PEG chemistries.
Storage and Handling
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Storage: Store at –20 °C in a sealed container, protected from light and moisture.
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Handling: Use under inert atmosphere when possible; prepare fresh solutions before use.
This product combines two reactive tosyl groups with a short PEG spacer, specifically offering a compact and versatile scaffold for nucleophilic substitution, PEGylation, and multifunctional conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
