Thiol-PEG2-Azide CAS:1365565-81-6 is a small molecule linker that contains three functional groups: a thiol group, a PEG (polyethylene glycol) chain, and an azide group. The thiol group can react with other molecules containing a maleimide or iodoacetamide group through a Michael addition reaction, forming a stable thioether linkage. The PEG chain can improve the solubility, stability, and biocompatibility of the linker, while the azide group can react with alkyne or cyclooctyne groups to form stable triazole linkages through a copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction.
Thiol-PEG2-Azide can be used in a wide range of bioconjugation applications, such as labeling of proteins, peptides, and other biomolecules, as well as surface modification of nanoparticles and other materials. Its unique combination of functional groups makes it a valuable tool in drug delivery and bioconjugation research, allowing for selective and stable attachment of molecules to specific targets. Learn more about other thiol peg azide.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
