TBTA Ligand (CAS 510758-28-8): Overview and Uses
TBTA (Tris(benzyltriazolylmethyl)amine) is a ligand used to enhance copper(I)-catalyzed azide-alkyne cycloaddition, known as click chemistry. It stabilizes the copper catalyst, making reactions faster and more efficient. TBTA is widely used in bioconjugation, chemical biology, and organic synthesis.
Key Features of TBTA:
- Formula: C27H27N7
- Molecular Weight: 449.55 g/mol
- CAS Number: 510758-28-8
- Role: Stabilizes copper, boosting click reaction speed and selectivity.
Applications:
- Click Chemistry: Enhances copper-catalyzed reactions for quick and efficient azide-alkyne coupling.
- Bioconjugation: Labels proteins, DNA, and other biomolecules for research and diagnostics.
- Chemical Biology: Aids in synthesizing biocompatible molecules for drug development.
- Organic Synthesis: Used to build complex molecules, including drugs and polymers.
- Material Science: Enables creation of advanced materials through precise molecular modifications.
Summary
TBTA ligand (CAS 510758-28-8) is crucial for enhancing click chemistry reactions, making it a key tool in bioconjugation, chemical biology, and material science. Its ability to stabilize copper catalysts improves reaction efficiency and selectivity, supporting a wide range of applications in research and synthesis.
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