SPDP-PEG12-acid Overview
SPDP-PEG12-acid is a versatile reagent used in biochemical research and drug development. It combines a PEG12 (polyethylene glycol) chain, an SPDP (N-Succinimidyl 3-(2-pyridyldithio)propionate) group, and an acid functionality. This combination makes it ideal for creating stable conjugates and controlled-release systems.
Key Features
- PEG12 Chain: Enhances solubility and flexibility for effective conjugation.
- SPDP Group: Forms stable disulfide bonds with thiol-containing molecules.
- Acid Functionality: Allows for further chemical modifications and linkage creation.
Applications
- Bioconjugation: Perfect for linking biomolecules like proteins, peptides, and antibodies with improved stability.
- Drug Delivery: Aids in developing targeted drug delivery systems with better pharmacokinetics.
- Controlled Release: Enables precise release of therapeutic agents via disulfide bond cleavage.
Advantages
- Improved Solubility: The PEG12 chain boosts solubility of conjugates.
- Stable Conjugates: SPDP ensures robust and stable disulfide bonds.
- Versatility: Acid functionality supports a range of chemical modifications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
