Propargyl-PEG2 Pyrene

Propargyl-PEG2-Pyrene

This product is a multifunctional PEG linker containing a terminal propargyl group, a PEG2 spacer, and a pyrene moiety. It specifically enables copper-catalyzed or copper-free click chemistry and provides strong fluorescence for probe development and imaging applications.

Key Features and Benefits

• Propargyl Group: Supports CuAAC or SPAAC click chemistry with azides.

• Pyrene Moiety: Provides strong fluorescence for detection and imaging.

• PEG2 Spacer: Enhances solubility and reduces steric hindrance.

• Dual Functionality: Combines click reactivity with fluorescent properties.

• High Purity: Ensures reproducibility in labeling workflows.

Applications

• Bioconjugation: Links azide-modified biomolecules with fluorescent handles.

• Probe Development: Builds multifunctional probes for diagnostics and imaging.

• Drug Delivery: Serves as a scaffold with orthogonal chemistry and fluorescence.

• Material Science: Functionalizes polymers and nanostructures with click and fluorescent properties.

Storage and Handling

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to light.

This product integrates alkyne click reactivity with pyrene fluorescence in a compact PEG2 scaffold, specifically offering a versatile tool for conjugation and imaging.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.