PLGA Ester Capped (50:50), MW 50K is a biodegradable copolymer with equal amounts of lactide and glycolide. It features ester end groups and an approximate molecular weight of 50 kDa. This polymer specifically supports controlled drug delivery and biomaterial development.
Key Features and Benefits
- Ester Capped: Provides ester end groups with reduced terminal carboxyl functionality.
- 50:50 PLGA Ratio: Combines lactide and glycolide equally for versatile biodegradable formulations.
- MW 50K: Balances polymer processability, matrix formation, and controlled-release performance.
- Biodegradable: PLGA hydrolyzes into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Supports particles, films, implants, scaffolds, and other biodegradable systems.
Applications
- Controlled Drug Delivery: Regulates drug release through biodegradable polymer matrices.
- Long-Acting Formulations: Supports depots, implants, and other sustained-release systems.
- Microparticles: Forms biodegradable microspheres and drug-loaded particles.
- Nanoparticles: Supports polymeric nanoparticles and biodegradable drug carriers.
- Biomaterials: Enables development of scaffolds, films, coatings, and polymer matrices.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize hydrolysis and polymer degradation.
PLGA Ester Capped (50:50), MW 50K combines moderate molecular weight with a balanced lactide:glycolide composition. Its ester end groups specifically support controlled drug delivery, particle formulation, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.