PLGA Ester Capped (50:50), MW 100K is a biodegradable copolymer with equal amounts of lactide and glycolide. It features ester end groups and an approximate molecular weight of 100 kDa. This polymer specifically supports sustained drug delivery and biomaterial development.
Key Features and Benefits
- Ester Capped: Provides ester end groups that reduce terminal carboxyl functionality.
- 50:50 PLGA Ratio: Combines lactide and glycolide equally for versatile biodegradable polymer formulations.
- MW 100K: Balances high molecular weight with practical processing and sustained-release performance.\Biodegradable: PLGA hydrolyzes into lactic acid and glycolic acid under physiological conditions.
- Versatile Polymer: Supports particles, films, implants, scaffolds, and other biodegradable delivery systems.
Applications
- Sustained Drug Delivery: Extends drug release through biodegradable polymer matrices.
- Long-Acting Formulations: Supports development of implants, depots, and other prolonged-release systems.
- Microparticles: Forms biodegradable microspheres and related drug-loaded particles.
- Biomaterials: Supports scaffolds, films, coatings, and durable biodegradable matrices.
- Formulation Research: Enables studies of polymer degradation, drug release, and molecular-weight-dependent PLGA performance.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to limit premature hydrolysis and polymer degradation.
PLGA Ester Capped (50:50), MW 100K combines ester end groups, high molecular weight, and a balanced lactide:glycolide composition to specifically support sustained drug delivery, long-acting formulations, durable polymer matrices, and advanced biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.