PLGA-di-acid, MW 5K is a low-molecular-weight biodegradable PLGA polymer featuring terminal carboxylic acid functionality where its reactive carboxyl groups and ~5 kDa molecular weight specifically support bioconjugation, polymer modification, drug delivery, and biomaterial applications.
Key Features and Benefits
- Carboxyl Functionalization: Provides reactive carboxylic acid groups for conjugation and derivatization.
- MW 5K: Low molecular weight supports efficient processing and flexible formulation development.
- Biodegradable: PLGA degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Conjugation: Carboxyl groups can be activated for coupling with amines and other nucleophiles.
- Difunctional Polymer: Terminal acid groups enable modification at both ends of the PLGA chain.
Applications
- Bioconjugation: Enables attachment of peptides, proteins, ligands, and other amine-containing molecules.
- Drug Delivery: Supports biodegradable drug delivery and controlled-release systems.
- Nanoparticles: Used to prepare functionalized polymeric nanoparticles and drug carriers.
- Polymer Modification: Provides carboxyl groups for further derivatization and linker attachment.
- Biomaterials: Suitable for biodegradable matrices, coatings, and related material research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA-di-acid, MW 5K combines low molecular weight, biodegradable PLGA, and terminal carboxyl functionality, specifically providing a versatile platform for bioconjugation, drug delivery, polymer modification, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.