PLGA-di-acid, MW 20K is a biodegradable PLGA polymer featuring terminal carboxylic acid functionality and an approximate molecular weight of 20 kDa where its reactive carboxyl groups specifically support bioconjugation, drug delivery, nanoparticle functionalization, and biomaterial applications.
Key Features and Benefits
- Carboxyl Functionalization: Provides reactive carboxylic acid groups for conjugation and derivatization.
- MW 20K: Moderate molecular weight supports efficient polymer processing and controlled-release formulations.
- Biodegradable: PLGA degrades into lactic acid and glycolic acid under physiological conditions.
- Versatile Conjugation: Carboxyl groups can be activated for coupling with amines and other nucleophiles.
- Difunctional Polymer: Terminal acid groups enable modification at both ends of the PLGA chain.
Applications
- Bioconjugation: Enables attachment of peptides, proteins, ligands, and other amine-containing molecules.
- Drug Delivery: Supports biodegradable controlled and sustained-release systems.
- Nanoparticles: Used to prepare functionalized polymeric nanoparticles and drug carriers.
- Polymer Modification: Provides carboxyl groups specifically for further derivatization and linker attachment.\
- Biomaterials: Suitable for biodegradable matrices, coatings, scaffolds, and related research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
PLGA-di-acid, MW 20K combines biodegradable PLGA with terminal carboxyl functionality, specifically providing a versatile polymer platform for bioconjugation, drug delivery, nanoparticle functionalization, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.