PCL-PEG-FITC, MW x 1K, n 2K is a fluorescently labeled amphiphilic block copolymer composed of poly(ε-caprolactone) (PCL) and polyethylene glycol (PEG) with fluorescein (FITC) functionality. This grade combines approximately 1K PCL with 2K PEG, providing a PEG-rich architecture for aqueous stabilization while enabling fluorescence-based detection and tracking.
Key Features and Benefits
- Amphiphilic Copolymer: Combines hydrophobic PCL with hydrophilic PEG for polymer assembly and drug delivery research.
- PCL MW 1K: Provides a short biodegradable hydrophobic segment for polymer assembly and hydrophobic interactions.
- PEG MW 2K: Provides a dominant hydrophilic segment for aqueous compatibility and steric stabilization.
- PEG-Rich Architecture: The 2:1 PEG-to-PCL molecular weight ratio favors hydrophilic surface character and stabilization of polymer assemblies.
- Fluorescent Label: FITC provides fluorescein-based fluorescence specifically for visualization and detection of labeled polymer systems.
- Optical Tracking: Enables fluorescence-based monitoring of polymer assemblies, nanoparticles, and biomaterial distribution.
Applications
- Fluorescent Nanoparticles: Supports preparation and visualization of fluorescently labeled nanoparticles and micelles.
- Drug Delivery Research: Enables fluorescence-based tracking of polymeric drug delivery systems.
- Cellular Studies: Supports investigation of cellular association, uptake, and localization of labeled polymer assemblies.
- Bioimaging Research: Provides fluorescent labeling for microscopy and other fluorescence-based analytical techniques.
- Biomaterial Research: Supports visualization and characterization of PCL-PEG-based biomaterial systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions and protected from light.
- Handling: Minimize exposure to light, moisture, and excessive heat to preserve polymer integrity and fluorescence performance.
PCL-PEG-FITC, MW x 1K, n 2K combines a short PCL block with a longer PEG segment and fluorescein functionality and specifically supports hydrophilically stabilized fluorescent polymer assemblies, nanoparticle tracking, cellular studies, and biomaterial imaging.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.