N-(Azido-PEG4)-biocytin
This product is a biotin derivative containing a PEG4 spacer and a terminal azide group. The biotin provides strong streptavidin/avidin binding, while the azide enables bioorthogonal click chemistry with alkynes, making it ideal for targeted labeling and multifunctional bioconjugation.
Key Features and Benefits:
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Biotin Moiety: Ensures high-affinity binding to avidin/streptavidin systems.
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Azide Group: Supports CuAAC and SPAAC click chemistry with alkyne partners.
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PEG4 Spacer: Enhances solubility and minimizes steric hindrance in conjugation.
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High Purity: Ensures reproducibility in sensitive labeling workflows.
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Dual Reactivity: Combines biotin affinity with click-enabled conjugation.
Applications:
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Affinity Labeling: Biotinylation of proteins, peptides, and biomolecules.
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Click Chemistry: Azide–alkyne ligation for orthogonal, dual-labeling strategies.
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Drug Delivery: Biotin-mediated targeting combined with orthogonal payload attachment.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and biosensors.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide functionality.
This product provides strong biotin binding combined with click-ready azide chemistry, making it an especially powerful tool for targeted labeling and advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
