MOTS-c (human) (trifluoroacetate salt) CAS：1627580‑64‑6
MOTS‑c (human) (trifluoroacetate salt) is a synthetic, stable trifluoroacetate salt form of human MOTS‑c, a 16‑amino‑acid mitochondrial‑derived peptide (MDP) encoded in the mitochondrial 12S rRNA gene. It is widely studied as a metabolic regulator and exercise mimetic with broad preclinical activity in metabolism, aging, and tissue protection.
Key Preclinical Research Applications
Metabolic Disorders: Improves insulin sensitivity, glucose tolerance, and lipid profiles; prevents high‑fat diet‑induced obesity and hyperinsulinemia in rodentsBertin. Aging & Longevity: Restores physical function, enhances healthspan, and mitigates age‑related metabolic decline. Cardiovascular Health: Attenuates myocardial remodeling, reduces vascular calcification, and improves cardiac function in preclinical models. Neurodegeneration: Protects against traumatic brain injury and supports dopaminergic neuron health. Musculoskeletal Health: Promotes osteogenic differentiation of mesenchymal stem cells and supports bone formation.
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