Methyltetrazine-SS-NHS is a cleavable, heterobifunctional linker featuring a tetrazine for bioorthogonal IEDDA reactions, a disulfide bond for controlled cleavage under reducing conditions, and an NHS ester for efficient amine-specific conjugation.
Key Features
- Methyltetrazine Group
Enables fast and selective bioorthogonal reactions with strained alkenes (e.g., trans-cyclooctene). - Disulfide Bond
Provides cleavable functionality for controlled molecule release in reducing environments. - NHS Ester Group
Reacts with primary amines to form stable amide bonds.
Methyltetrazine-SS-NHS Applications
- Bioconjugation
Ideal for labeling biomolecules with dual functionality. - Controlled Release Systems
Supports applications requiring reversible conjugation. - Molecular Imaging and Diagnostics
Facilitates the development of functional imaging agents. - Drug Delivery
Enables the design of targeted and cleavable therapeutic conjugates.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
