Methyltetrazine-amido-PEG5-alkyne CAS:2322322-23-4 is a versatile, bifunctional linker molecule. It is widely utilized in pharmaceutical research and development for bioconjugation applications, where it serves as a bridge between molecules with distinct functional groups.
The methyltetrazine moiety of Methyltetrazine-amido-PEG5-alkyne facilitates rapid, highly-selective bioorthogonal reactions, such as the inverse electron-demand Diels-Alder reaction with strained alkenes or alkynes. The amido-PEG5 spacer enhances solubility, biocompatibility, and reduces steric hindrance while providing an adequate linker length. The alkyne group enables click chemistry conjugation with azides, providing a robust platform for constructing complex bioconjugates. This linker has been widely employed in the development of targeted drug delivery systems, antibody-drug conjugates, and imaging probes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
