Methyltetrazine-PEG8-PFP ester contains a PFP ester and a methyltetrazine group. This compound readily react with amines, such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slightly basic pH to form amide bond. The resulting tetrazine bearing molecule can easily react with a TCO tagged biomolecule. The hydrophilic PEG spacer can increase the hydrophilic properties of the compound.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.