Mal-PEG-HZ, MW 5K (Maleimide-PEG-Hydrazide) contains two functional groups: a maleimide group (-CO-NH-CH=CH2) and a hydrazide group (-NH-NH2).
The maleimide group is known for its ability to react selectively with thiol-containing molecules, such as cysteine residues on proteins, forming stable thioether bonds. This property has made Mal-PEG-HZ, MW 5K a useful tool in the development of site-specific protein conjugation, which allows for the precise attachment of therapeutic agents to proteins, enhancing their efficacy and reducing off-target effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.