HO-PEG1-t-butyl ester
This product is a high-purity monofunctional PEG linker with a terminal hydroxyl and an acid-labile tert-butyl ester, connected by a short PEG1 spacer that offers minimal steric hindrance, hydrophilicity, and versatility for functionalization.
Key Features
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Monofunctional PEG with terminal hydroxyl and t-butyl ester groups
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Acid-labile t-butyl ester for controlled carboxylic acid generation
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Short PEG1 spacer for minimal steric impact and preserved solubility
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High chemical purity for reliable synthesis performance
Applications
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Synthesis of functional PEG derivatives
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Prodrug and polymer–drug conjugate design
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Biomolecule and surface modification
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Material and nanoparticle engineering with short hydrophilic spacers
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Warm to room temperature before opening
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Avoid repeated freeze–thaw cycles
This product combines a reactive hydroxyl group with an acid-cleavable tert-butyl ester, connected by a short PEG1 chain specifically for compact, hydrophilic linker applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
