Folate PEG linker serves as an excellent target oriented molecular probe. Folic acid PEG linkers have improved aqueous solubility compared to their non-PEG versions. They have been widely used in target drug delivery and MRI imaging applications. The PEG spacer increase the solubility of the resulting complex in aqueous media.
Folate PEG3 NHS ester has been extensively utilized in the development of targeted drug delivery systems for cancer therapy. Its unique chemical properties allow for the covalent attachment of therapeutic agents, such as chemotherapy drugs, to the PEG chain via the reactive NHS ester group. The resulting conjugates exhibit enhanced cellular uptake and retention in cancer cells that overexpress folate receptors, leading to improved therapeutic efficacy and reduced toxicity to healthy tissues.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.