Fmoc-L-Lys(Mca)-OH
Description:
Fmoc-L-Lys(Mca)-OH is a specialized reagent used in peptide synthesis and fluorescence-based applications, combining an Fmoc protective group with a fluorescent Mca tag for enhanced peptide analysis.
- Fmoc: Fluorenylmethyloxycarbonyl, protects the lysine amino group during synthesis.
- Lys: Lysine, an amino acid with a reactive side chain.
- Mca: 7-Methoxycoumarin-4-acetic acid, a fluorescent dye.
Key Features:
- Protective Group: Fmoc shields lysine’s amino group, enabling precise synthesis.
- Fluorescent Tag: Mca provides strong fluorescence for detection.
- Absorption: 322 nm
- Emission: 384 nm
- Quantum Yield: 0.45 (at 3.1 μM)
Applications:
- Peptide Synthesis: Incorporates fluorescently tagged lysine in solid-phase peptide synthesis.
- Fluorescent Assays: Ideal for assays requiring fluorescence for sensitive peptide detection and quantification.
Benefits:
- Enhanced Detection: Mca’s fluorescence enables precise quantification.
- Controlled Synthesis: Fmoc protection minimizes side reactions for accurate peptide creation.
Summary:
Fmoc-L-Lys(Mca)-OH is essential in peptide chemistry, combining protective and fluorescent tagging functions. Mca offers strong fluorescence, with absorption at 322 nm and emission at 384 nm, and a quantum yield of 0.45, enhancing detection in peptide synthesis and assays.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
