DNP-PEG12-acid
This product is a heterobifunctional linker that contains a dinitrophenyl (DNP) hapten for antibody recognition and a terminal carboxylic acid for amide coupling. The PEG12 spacer improves hydrophilicity, flexibility, and spacing, making it especially valuable for immunology, probe design, and multifunctional conjugation.
Key Features and Benefits:
-
DNP Moiety: Functions as a hapten for antibody binding in immunological studies.
-
Carboxylic Acid: Couples efficiently with amines to form stable amide linkages.
-
PEG12 Spacer: Enhances solubility, reduces steric hindrance, and increases accessibility.
-
High Purity: Ensures reproducibility in sensitive labeling workflows.
-
Dual Functionality: Combines antibody recognition with versatile coupling chemistry.
Applications:
-
Immunology Research: Biotin-free hapten labeling for antibody response studies.
-
Probe Development: Builds DNP-tagged probes for imaging and molecular tracking.
-
Bioconjugation: Couples to proteins, peptides, or nanoparticles with amide bonds.
-
Drug Delivery: PEGylated scaffold improves solubility and stability of conjugates.
Storage and Handling:
-
Storage: Store at –20 °C in a moisture- and light-protected container.
-
Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve acid reactivity.
This product provides hapten recognition and coupling capability in a long PEG framework, making it an especially versatile tool for immunology and bioconjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
