DMG-PEG, MW 550 is an amphiphilic lipid-PEG conjugate containing a hydrophobic DMG lipid anchor and compact hydrophilic PEG segment with MW 550, while its short PEG chain supports lipid nanoparticle formulation, liposome research, surface PEGylation, and biomaterial development.
Key Features and Benefits
- Amphiphilic Structure: DMG-PEG combines a hydrophobic lipid anchor with a hydrophilic PEG segment.
- PEG MW 550: The PEG 550 segment provides hydrophilic character while maintaining a short and compact chain length.
- DMG Lipid Anchor: Dimyristoyl glycerol provides two saturated C14 lipid chains that specifically support incorporation into lipid-based assemblies.
- PEGylated Lipid Platform: The PEG segment provides a hydrophilic component for developing PEG-containing lipid systems.
- Lipid Assembly Capability: The hydrophobic DMG anchor specifically promotes association with compatible lipid membranes and assemblies.
- Surface PEGylation: DMG-PEG can introduce short PEG chains onto compatible lipid-based surfaces and nanoparticles.
- Formulation Versatility: Its amphiphilic architecture supports research involving liposomes, lipid nanoparticles, and other lipid-based formulations.
- Biomaterial Platform: DMG and PEG specifically provide complementary hydrophobic and hydrophilic properties for lipid-based biomaterial research.
Applications
- Lipid Nanoparticle Research: DMG-PEG, MW 550 supports formulation and investigation of PEG-containing lipid nanoparticle systems.
- Liposome Research: Supports preparation and modification of liposomes and related lipid assemblies.
- PEGylation Research: Provides a lipid-linked PEG component for studying PEGylated lipid systems.
- Nanoparticle Formulation: Supports development of lipid-based nanoparticles containing a compact hydrophilic PEG segment.
- Lipid Assembly Research: Enables investigation of amphiphilic lipid organization and self-assembled structures.
- Surface Modification: Supports short-chain PEG presentation on compatible lipid and nanomaterial surfaces.
- Drug Delivery Research: Provides an amphiphilic lipid-PEG component specifically for experimental delivery-system development.
- Biomaterial Research: Supports development of PEGylated lipid materials and related biomaterial systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
DMG-PEG, MW 550 combines a hydrophobic DMG lipid anchor with a compact hydrophilic PEG segment, while its short PEG chain provides a versatile platform for lipid formulation, surface PEGylation, and biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
