DMG-PEG, MW 1K is an amphiphilic lipid-PEG conjugate containing a hydrophobic DMG lipid anchor and hydrophilic 1K PEG segment, while its compact PEG chain supports lipid nanoparticle formulation, liposome research, surface PEGylation, and biomaterial development.
Key Features and Benefits
- Amphiphilic Structure: DMG-PEG combines a hydrophobic lipid anchor with a hydrophilic PEG segment.
- PEG MW 1K: The 1K PEG segment provides hydrophilic character while maintaining a relatively compact PEG chain length.
- DMG Lipid Anchor: Dimyristoyl glycerol provides two saturated C14 lipid chains that support incorporation into lipid-based assemblies.
- PEGylated Lipid Platform: The PEG segment specifically provides a hydrophilic component for developing PEG-containing lipid systems.
- Lipid Assembly Capability: The hydrophobic DMG anchor promotes association with compatible lipid membranes and assemblies.
- Surface PEGylation: DMG-PEG can introduce PEG chains onto compatible lipid-based surfaces and nanoparticles.
- Formulation Versatility: Its amphiphilic architecture supports research specifically involving liposomes, lipid nanoparticles, and other lipid-based formulations.
- Biomaterial Platform: DMG and PEG specifically provide complementary hydrophobic and hydrophilic properties for lipid-based biomaterial research.
Applications
- Lipid Nanoparticle Research: DMG-PEG, MW 1K supports formulation and investigation of PEG-containing lipid nanoparticle systems.
- Liposome Research: Supports preparation and modification of liposomes and related lipid assemblies.
- PEGylation Research: Provides a lipid-linked PEG component for studying PEGylated lipid systems.
- Nanoparticle Formulation: Supports development of lipid-based nanoparticles containing a hydrophilic PEG component.
- Lipid Assembly Research: Enables investigation of amphiphilic lipid organization and self-assembled structures.
- Surface Modification: Supports PEG presentation on compatible lipid and nanomaterial surfaces.
- Drug Delivery Research: Provides an amphiphilic lipid-PEG component for experimental delivery-system development.
- Biomaterial Research: Supports development of PEGylated lipid materials and related biomaterial systems.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry conditions.
- Handling: Protect from moisture and excessive heat. Allow the material to reach room temperature before opening to minimize condensation.
DMG-PEG, MW 1K combines a hydrophobic DMG lipid anchor with a compact hydrophilic PEG segment and specifically provides a versatile amphiphilic lipid for nanoparticle formulation, liposome research, PEGylation, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
