DBCO-PEG9-amine
This product is a heterobifunctional linker featuring a dibenzocyclooctyne (DBCO) group for copper-free SPAAC click chemistry and a terminal amine for versatile coupling. The PEG9 spacer provides excellent solubility, flexibility, and spacing, making it especially useful in bioconjugation, probe development, and drug delivery.
Key Features and Benefits:
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DBCO Group: Enables rapid, copper-free click reactions with azides.
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Terminal Amine: Couples efficiently with activated esters and electrophiles.
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PEG9 Spacer: Enhances solubility, hydrophilicity, and steric accessibility.
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Dual Reactivity: Supports orthogonal conjugation strategies.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Links azide-modified and amine-reactive biomolecules.
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Drug Delivery: Builds PEGylated, bioorthogonal drug carriers.
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Probe Development: Creates multifunctional imaging and diagnostic probes.
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Material Science: Functionalizes polymers, nanoparticles, and biomaterials.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF); avoid prolonged exposure to moisture.
This product combines copper-free click chemistry with amine coupling in a PEG9 scaffold, specifically offering versatile reactivity for conjugation, probe design, and therapeutic development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
