DBCO-PEG6-NHS ester contains a NHS (N-hydroxysuccinimide) ester functional group, which is commonly used for the covalent conjugation of molecules to primary amines. In addition, DBCO (dibenzocyclooctyne) is a cyclooctyne functional group that reacts selectively with azide groups through a copper-free click chemistry reaction, allowing for the rapid and efficient modification of biomolecules. Click here for more DBCO NHS ester.
In the field of pharmaceutical research and development, DBCO-PEG6-NHS ester has been widely used in the design and development of drug delivery systems. By functionalizing drug molecules with PEG and DBCO moieties, the resulting conjugates exhibit improved solubility, stability, and circulation time in vivo, leading to enhanced therapeutic efficacy and reduced toxicity. Moreover, the click chemistry reaction between DBCO and azide groups allows for the rapid and selective modification of biomolecules, enabling the development of multifunctional drug delivery systems with precise control over the drug release rate and targeting ability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
