DBCO-PEG6-amine
This product is a heterobifunctional linker featuring a dibenzocyclooctyne (DBCO) for copper-free SPAAC click chemistry and a terminal amine for versatile conjugation. The PEG6 spacer enhances solubility, flexibility, and spacing, making it especially useful for bioconjugation, probe design, and drug delivery.
Key Features and Benefits:
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DBCO Group: Enables rapid, catalyst-free click chemistry with azides.
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Terminal Amine: Couples efficiently with activated esters or electrophiles.
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PEG6 Spacer: Provides solubility, hydrophilicity, and steric accessibility.
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Dual Reactivity: Supports orthogonal conjugation workflows.
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High Purity: Ensures reproducible results in sensitive applications.
Applications:
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Bioconjugation: Links azide-modified and amine-reactive biomolecules.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Creates PEGylated drug carriers with bioorthogonal reactivity.
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Material Science: Functionalizes polymers, nanoparticles, and surfaces.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid prolonged exposure to moisture.
This product integrates bioorthogonal DBCO chemistry with amine reactivity in a PEG6 chain, making it an especially versatile linker for advanced conjugation and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
