DBCO-PEG4-MMAF (CAS: 2360411-65-8) is a powerful bioconjugation molecule. It consists of three key components: DBCO (dibenzocyclooctyne), tetraethylene glycol spacer, and MMAF (monomethyl auristatin F), a cytotoxic agent. This combination creates a highly effective system for targeted drug delivery. The DBCO group allows for fast, copper-free click chemistry, ensuring efficient attachment to targeting ligands like antibodies. This structure enhances the selectivity and efficacy of cancer therapies.
Applications:
- Targeted Cancer Treatment: Delivers cytotoxic agents directly to cancer cells, minimizing collateral damage.
- Bioconjugation: Links antibodies or ligands to therapeutic agents for selective drug delivery.
- Click Chemistry: Enables copper-free, strain-promoted reactions for drug design.
- Drug Development: Essential for creating next-gen ADCs with higher precision.
- Precision Medicine: Advances highly specific cancer therapies that improve patient outcomes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
