DBCO-PEG-acid, MW 5K is a linear heterobifunctional PEG derivative. DBCO-PEG-acid is one of Axispharm‘ reactive Click Chemistry PEG reagents with a terminal carboxylic group. DBCO (dibenzocyclooctyne) is a cyclooctyne with excellent reactivity toward azide group. The strainpromoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution with high efficiency.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.