DBCO-amine CAS:1255942-06-3, or dibenzocyclooctyne-amine, is a bifunctional molecule featuring a strained cyclooctyne ring and an amine group. As a bioorthogonal click chemistry tools, DBCO-amine enables rapid, selective, and efficient conjugation to azide-containing biomolecules without the need for toxic catalysts or harsh conditions. This non-invasive chemical tool has become instrumental in streamlining various labeling and modification processes in biological systems.
Introduction to the application:
In pharmaceutical research and development, DBCO-amine plays a crucial role in designing bioconjugates, such as antibody-drug conjugates, drug carriers, and imaging probes. Through its ability to form stable triazole linkages with azide-functionalized molecules, DBCO-amine has significantly advanced drug discovery, target identification, and in vivo imaging studies. Its use in bioorthogonal click chemistry has opened up new avenues for investigating cellular processes, ultimately leading to the development of innovative therapeutics and diagnostics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.