BCN-PEG4-acid (CAS 2226472-38-2) is a specialty chemical used mainly in bioconjugation and drug delivery. It contains a BCN group and a carboxylic acid group, allowing for copper-free click chemistry. This compound has a polyethylene glycol (PEG) chain, extended to four units (PEG4), enhancing water solubility, bioavailability, and reducing immunogenicity of compounds. The PEG4 provides optimal length and flexibility for molecule conjugation. The BCN part allows reactions with azides, beneficial in biological systems sensitive to copper, while the carboxylic acid end offers a site for further conjugation, like forming amide bonds with amines.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
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