Azide-PEG2-Ms linker contains an azide group and a mesyl group. The PEG spacer increases the aqueous solubility of the resulting compound. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The mesyl group is good leaving group and undergoes nucleophilic substitutions with thiol and amine group. It can also be used as protecting groups for primary alcohols.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.