Azido-PEG4-nitrile is a PEG derivative which contains an azido group and a nitrile group. The azido group is commonly used in Click Chemistry reactions with alkynes, DBCO and BCN to produce triazole linkages. The nitrile group can undergo hydrolysis to form amide and carboxylic acid. It can also undergo reduction to form primary amine. The hydrophilic PEG spacer can increase the solubility in aqueous media.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.