APDye 488 Picolyl Azide

APDye 488 Picolyl Azide

This product is a bright, green-fluorescent dye containing a picolyl azide group for bioorthogonal labeling. It provides enhanced copper-catalyzed click reactivity compared to standard azides, making it especially ideal for efficient conjugation in biological and imaging applications.

Key Features and Benefits

• Bright Fluorescence: Excitation/emission ~495/520 nm, ideal for green channel imaging.

• Picolyl Azide: Enhances CuAAC efficiency over traditional azides.

• High Sensitivity: Provides strong signal intensity in labeling experiments.

• Bioorthogonal Chemistry: Compatible with alkyne-modified biomolecules.

• High Purity: Ensures reliable and reproducible fluorescence performance.

Applications

• Fluorescence Imaging: Labels alkyne-modified proteins, nucleic acids, or glycans.

• Probe Development: Builds fluorescent probes using click chemistry.

• Bioconjugation: Couples biomolecules via copper-catalyzed azide–alkyne cycloaddition.

• Diagnostics: Enables sensitive detection assays in molecular biology.

Storage and Handling

• Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Protect from prolonged light exposure; prepare fresh solutions before use.

This product combines bright green fluorescence with an enhanced azide for efficient CuAAC click labeling, specifically offering a powerful tool for imaging and bioconjugation.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.