8-Arm PLGA-N3, MW 10K is a biodegradable multi-arm PLGA polymer with eight azide-functionalized arms and an approximate molecular weight of 10 kDa where its branched architecture specifically enables click chemistry, multivalent conjugation, drug delivery, and biomaterial applications.
Key Features and Benefits
- 8-Arm Architecture: Provides a branched polymer structure with multiple reactive arms.
- Azide Functionalization: Offers terminal azide groups for selective bioorthogonal conjugation.
- MW 10K: Low molecular weight supports efficient processing and flexible formulation development.
- Click Chemistry: Compatible with alkynes and strained cyclooctynes for CuAAC or copper-free SPAAC reactions.
- Multivalent Reactivity: Multiple azide groups specifically enable efficient conjugation, crosslinking, and multifunctional modification.
Applications
- Click Chemistry: Enables conjugation with alkyne- or DBCO-functionalized molecules.
- Bioconjugation: Supports attachment of peptides, proteins, ligands, dyes, and other functional molecules.
- Drug Delivery: Suitable for biodegradable functionalized drug delivery systems.
- Crosslinking: Enables formation of polymer networks using complementary click-reactive compounds.
- Biomaterials: Used in hydrogels, nanoparticles, scaffolds, coatings, and tissue engineering research.
Storage and Handling
- Storage: Store at –20 °C in a sealed, dry container.
- Handling: Protect from moisture and excessive heat to minimize premature hydrolysis and polymer degradation.
8-Arm PLGA-N3, MW 10K combines biodegradable PLGA with multivalent azide functionality, providing an especially versatile platform for click chemistry, bioconjugation, crosslinking, drug delivery, and biomaterial development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.