2′-OMe-Ac-C Phosphoramidite

2′-OMe-Ac-C Phosphoramidite (CAS: 199593-09-4) is a modified cytidine phosphoramidite used in RNA and DNA synthesis. It features a 2′-O-methyl modification on the ribose sugar and an acetyl-protected cytidine base. This modification enhances the stability and resistance to nucleases in synthetic oligonucleotides, making it ideal for antisense oligonucleotides, siRNA, and other RNA-related research.

Applications:

• RNA Synthesis: Adds 2′-O-methyl cytidine into synthetic RNA strands for increased stability.
• Oligonucleotide Stability: Enhances nuclease resistance in synthetic oligonucleotides.
• Gene Silencing: Useful in siRNA and antisense oligonucleotide research.