β‑Lapachone is a natural ortho‑naphthoquinone isolated from Tabebuia avellanedae. It exerts potent anticancer activity via NQO1‑mediated futile redox cycling, generating ROS, inducing DNA damage, PARP‑1 hyperactivation, and NAD⁺/ATP depletion, leading to selective death of NQO1‑overexpressing tumor cells. It also shows anti‑inflammatory, antimicrobial, and neuroprotective effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
