MC-DM1 CAS:1375089-56-7 is a cutting-edge drug-linker molecule, composed of the MC linker and the toxic moiety DM1 (Mertansine). DM1, a thiol-containing maytansinoid, is a potent disruptor of microtubules that exhibits significant cytotoxic properties. The MC-DM1 complex enables efficient conjugation with antibodies for the development of next-generation antibody-drug conjugates (ADCs).
Introduction to the application:
In the realm of pharmaceutical research and development, MC-DM1 plays a pivotal role in creating ADCs for targeted cancer therapy. The innovative MC-DM1 complex facilitates the precise delivery of the potent DM1 cytotoxic agent to cancer cells, improving treatment efficacy while minimizing off-target effects. The robust MC linker ensures stability in the bloodstream and selective release of DM1 within tumor cells, contributing to the development of safer and more effective anticancer treatments.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.