HO-PEG12-t-butyl ester
This product is a high-purity monofunctional PEG derivative with a hydroxyl group for further functionalization and a t-butyl ester-protected carboxyl group for controlled deprotection under mild acidic conditions. The PEG12 spacer specifically enhances solubility in aqueous and organic media while minimizing steric hindrance, making it suitable for a variety of chemical and bioconjugation workflows.
Key Features
-
Hydroxyl group for versatile chemical modification
-
t-Butyl ester for acid-labile carboxyl protection
-
PEG12 spacer for high solubility and low immunogenicity
Applications
-
Synthesis of functionalized PEG derivatives
-
Prodrug development and polymer modification
-
Biomolecule conjugation and material surface engineering
Storage and Handling
-
Store at –20 °C, protected from light and moisture
-
Warm to room temperature before use to avoid moisture condensation
This product offers a protected carboxyl group for controlled release and a hydroxyl group for diverse coupling chemistries. The PEG12 backbone provides excellent solubility and biocompatibility, making it an especially adaptable reagent for advanced synthesis and bioconjugation projects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
