PCL-PEG-Rhodamine B (PCL-PEG-RhB), MW x 10K, n 2K is a fluorescent amphiphilic block copolymer containing a Rhodamine B fluorophore. It combines a 10K poly(ε-caprolactone) (PCL) block with a 2K polyethylene glycol (PEG) block, providing an especially strong PCL-rich architecture for hydrophobic assembly and a fluorescent label for visualization and tracking.
Key Features and Benefits
- Fluorescent Amphiphilic Copolymer: Combines hydrophobic PCL, hydrophilic PEG, and Rhodamine B fluorescence in one polymer construct.
- PCL MW 10K: Provides a substantial biodegradable hydrophobic block for core formation and incorporation of hydrophobic compounds.
- PEG MW 2K: Provides a shorter hydrophilic segment specifically for aqueous compatibility and interfacial stabilization.
- PCL-Rich Architecture: The 5:1 PCL-to-PEG molecular weight ratio favors hydrophobic interactions and core-forming polymer assemblies.
- Rhodamine B Label: Provides visible-region fluorescence suitable for imaging and fluorescence-based tracking studies.
- Fluorescent Tracking: Enables visualization of polymer distribution, nanoparticle uptake, localization, and transport in research systems.
Applications
- Fluorescent Nanoparticles: Supports preparation and visualization of fluorescently labeled nanoparticles, micelles, and polymer assemblies.
- Drug Delivery Research: Enables fluorescence-based tracking of PCL-rich polymeric carriers and hydrophobic drug delivery systems.
- Cellular Uptake Studies: Supports fluorescence microscopy and studies of nanoparticle or polymer internalization.
- Biodistribution Research: Enables tracking of labeled polymer carriers in suitable in vitro and in vivo research models.
- Biomaterial Imaging: Supports visualization and localization of polymeric materials in biomaterial and tissue-engineering research.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry, light-protected conditions.
- Handling: Protect from light, moisture, and excessive heat to maintain polymer integrity and fluorescence performance.
This product combines a strongly PCL-rich architecture with Rhodamine B fluorescence and specifically supports fluorescent nanoparticle preparation, carrier tracking, cellular uptake studies, and hydrophobic drug delivery research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.