PCL-PEG-Rhodamine B (PCL-PEG-RhB), MW x 3K, n 3K is a fluorescent amphiphilic block copolymer composed of poly(ε-caprolactone), polyethylene glycol, and a Rhodamine B fluorophore. The equal 3K PCL and 3K PEG blocks provide balanced hydrophobic-hydrophilic character for self-assembly, while Rhodamine B enables fluorescence-based visualization and tracking.
Key Features and Benefits
- Fluorescent Amphiphilic Copolymer: Integrates hydrophobic PCL, hydrophilic PEG, and a fluorescent Rhodamine B label.
- PCL MW 3K: Provides a biodegradable hydrophobic block for nanoparticle or micelle core formation and hydrophobic cargo incorporation.
- PEG MW 3K: Provides a hydrophilic block specifically for aqueous compatibility, surface hydration, and steric stabilization.
- Balanced Block Ratio: Equal PCL and PEG molecular weights provide balanced hydrophobic and hydrophilic character for amphiphilic assembly.
- Rhodamine B Fluorescence: Provides a fluorescent signal for visualization and tracking of polymer-containing formulations.
- Carrier Tracking: Enables investigation of nanoparticle localization, cellular uptake, intracellular trafficking, and polymer distribution.
Applications
- Fluorescent Nanoparticles: Preparation of Rhodamine B-labeled polymeric nanoparticles, micelles, and related assemblies.
- Drug Delivery Research: Enables fluorescence-based tracking of polymeric drug delivery systems and hydrophobic cargo carriers.
- Cellular Uptake Studies: Supports fluorescence-based evaluation of polymer or nanoparticle internalization.
- Biodistribution Research: Enables tracking of fluorescent polymer carriers in suitable experimental models.
- Biomaterial Imaging: Supports visualization of polymer localization and transport in biomaterial and tissue-engineering studies.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry, light-protected conditions.
- Handling: Protect from light, moisture, and excessive heat to preserve polymer integrity and fluorescence performance.
This product combines balanced PCL and PEG blocks with Rhodamine B fluorescence and specifically supports traceable polymeric assemblies for nanoparticle imaging, cellular uptake, localization, and drug delivery research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.