PCL-PEG-Rhodamine B (PCL-PEG-RhB), MW x 5K, n 5K is a fluorescent amphiphilic block copolymer containing a Rhodamine B fluorophore. It combines a 5K poly(ε-caprolactone) (PCL) block with a 5K polyethylene glycol (PEG) block, providing an especially balanced hydrophobic-hydrophilic architecture for amphiphilic assembly and fluorescence-based visualization and tracking.
Key Features and Benefits
- Fluorescent Amphiphilic Copolymer: Combines hydrophobic PCL, hydrophilic PEG, and Rhodamine B fluorescence in one polymer construct.
- PCL MW 5K: Provides a biodegradable hydrophobic segment for core formation and incorporation of hydrophobic compounds.
- PEG MW 5K: Provides a hydrophilic segment specifically for aqueous compatibility and steric stabilization.
- Balanced Block Ratio: Equal PCL and PEG molecular weights provide balanced hydrophobic and hydrophilic character for amphiphilic assembly.
- Rhodamine B Label: Provides visible-region fluorescence for imaging and fluorescence-based tracking studies.
- Fluorescent Tracking: Enables visualization of polymer distribution, nanoparticle uptake, localization, and transport in research systems.
Applications
- Fluorescent Nanoparticles: Supports preparation and visualization of fluorescently labeled nanoparticles, micelles, and polymer assemblies.
- Drug Delivery Research: Enables formulation and fluorescence-based tracking of polymeric drug delivery systems.
- Cellular Uptake Studies: Supports fluorescence microscopy and studies of nanoparticle or polymer internalization.
- Biodistribution Research: Enables tracking of labeled polymer carriers in suitable in vitro and in vivo research models.
- Biomaterial Imaging: Supports visualization and localization of polymeric materials in biomaterial and tissue-engineering research.
Storage and Handling
- Storage: Store at –20 °C in a tightly sealed container under dry, light-protected conditions.
- Handling: Protect from light, moisture, and excessive heat to maintain polymer integrity and fluorescence performance.
This product combines balanced PCL and PEG blocks with Rhodamine B fluorescence and specifically supports fluorescent nanoparticle preparation, carrier tracking, cellular uptake studies, and drug delivery research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.